Sunday, 16th February 41st Lorne Genome Conference 2020

Conference Welcome: Scott Cohen, 2020 Convenor 

Aboriginal Acknowledgement of Country: Marnie Blewitt 

• Towards forecasting tumor progression: From genomic insights to predictive modeling - Christina Curtis

• Genome diversity and instability in the human germline - Eva Hoffmann
• Medical genomics and Australians of Aboriginal and/or Torres Strait Islander descent - Simon Easteal
• Regulation of gene repression by post-translational modifications in polycomb repressive complexes - Samuel C Agius
• H2A.Z and the p400 complex play dynamic roles to regulate centromere function - Yasmin Dijkwel
• Long read sequencing illuminates the repetitive genome and points to upstream SINEs as an explanation for LINE-1 locus hyperactivity - Nathan Smits
• Identifying oncogene-specific cancer-immune cell interactions in acute myeloid leukaemia from in silico deconvolution of bulk patient bone marrow samples - Jasmin Straube

• Epigenetic reprogramming at estrogen-receptor binding sites alters the 3D chromatin landscape in endocrine resistant breast cancer - Joanna Achinger-Kawecka
• New genes that control transplant rejection identified through an in vivo CRISPR activation screen  - Sumire Antonioli
• Could exon skipping become a treatment for recessive Ullrich Congenital Muscular Dystrophy - May Aung-Htut
• The cis-regulatory code of response to combined heat and drought stress in Arabidopsis thaliana - Christina B Azodi
• A comprehensive survey of Alu repeat diversity in humans - Renzo Balboa
• Uncovering the missing pieces of the haemoglobin switching puzzle - Henry W Bell
• Investigation of how the epigenetic regulator Smchd1 regulates Hox gene expression - Natalia Benetti
• Regulation of neural stem cells and cortex development by histone acetylation - Maria I Bergamasco
• Interactions between FUS and RNA G-quadruplexes in Alzheimer's disease - Uditi Bhatt
• FGF and MAPK regulate distinct aspects of male germline development - Rheannon Blucher
• Molecular mechanisms controlling the emergence of antimicrobial drug resistance in mismatch repair mutants - Kylie Boyce
• For FOX sake: Using Treg-specific datasets to study mechanisms of autoimmunity in human tissues - James Breen
• Roles of 5-Methylcytosine (m⁵C) RNA modification in embryonic stem cells - Michael Bullen
• Rescue of Fibrillin-1 Microfibril Formation in Fibroblasts from Individuals with Marfan Syndrome - Jessica M Cale
•   Discrete waves of genome restructuring during B cell clonal expansion occur independent of cell division and DNA synthesis - Wing Fuk Chan
• Exploiting chromatin organisation in circulating tumour DNA to track non-genomic evolution in cancer - Dineika Chandrananda
• Identifying functional pseudogenes in the human transcriptome by long-read cDNA sequencing - Seth W Cheetham
• Insight into cell identity from building integrated trascriptional atlases - Jarny Choi
• Comparative value of droplet-based Single-Cell RNA-Seq platforms to extract functional outputs in highly complex tissues. - Yolanda Colino-Sanguino
• Transcriptional dysregulation underlies severe childhood speech disorder - Matthew Coleman
• The C. elegans TRIM protein NHL-2 regulates stem cell development through let-7 miRNA pathways - Rhys Colson
• Evaluation of drug sensitivity in neuroblastoma cells that lack telomere maintenance mechanisms - Dale Cross
• Histone demethylome map reveals combinatorial gene regulatory functions of histone demethylases in embryonic stem cells - Partha Pratim Das
• Identification and long-read sequencing of neuropsychiatric disorder risk genes in human brain - Ricardo De Paoli-Iseppi
• Prevention of transcription-associated DNA damage by removal of DNA:RNA hybrids - Andrew J Deans
• SpliSER: A simple yet powerful way to quantify splicing - Craig Dent
• Barcoding and demultiplexing Oxford Nanopore native RNA sequencing reads with deep residual learning - James M Ferguson
• Patterns of gene expression and gene regulation across genomically and geographically distinct populations in Indonesia - Irene Gallego Romero
• Identification of Protein Factors Associated with the ALTernative Lengthening of Telomeres - Andrew Garvie
• A direct role for BRG1 chromatin remodeling in DNA replication - Katherine A Giles
• Ultra-Rapid and accurate data analysis solution for TSO500 ctDNA: Enabling comprehensive genomic profiling with a plasma-based assay - Gerald Goh
• The landscape of circular RNA expression in the human brain - Akira Gokool
• Context determines the outcome - how miR-200 switches from being an epithelial specifier to a promoter of sympathoadrenal neuron differentiation and neuroblastoma suppressor - Gregory J Goodall
• Maternal Smchd1 is required for imprinted X chromosome inactivation - Quentin Gouil
• Features on the mRNA that allow RNase III family protein to cleave in the mouse embryonic stem cells  - Karen Gu
• Clostridium perfringens: friend or foe? - Emily L Gulliver
• Temperature and epigenetics in bearded dragon sex determination - Benjamin Hanrahan
• High resolution analysis of long non-coding RNA isoforms in mouse cortex - Simon A Hardwick
• Sex-specific neuroprotection by antisense-Sry inhibition in experimental Parkinson's disease - Vincent Harley
• The role of the DNA damage response in telomerase recruitment to telomeres - Ashley Harman
• Kaleidoscopic impact of ZBTB18 missense variants underlies human brain development and disease. - Julian Heng
• Opportunities and challenges of analysing multi-regional tumour biopsies to characterise heterogeneity in cancer - Sebastian Hollizeck
• Stochastic class switch recombination of the Igh locus is driven by clonal variability in expression of AID and transcription of germline non-coding RNAs - Miles Horton
• The molecular bases of RNA silencing by CRISPR-Cas13 - Wenxin Hu
• The role of G-quadruplexes in telomere lengthening and genome instability in ALT cells - Meng-Ping Hsu
• Investigating the epigenetic regulator Smchd1 as a potential drug target for the treatment of Prader-Willi Syndrome - Megan Iminitoff
• Effect of transposon activation in fruit fly ovary development  - Ali Afrasiabi
• Increased Nanopore and PacBio single cell sequencing output with MiRCL-seq  - Jafar S. Jabbari
• Determining the role of PRC2 in oocyte epigenetic programming and offspring health - Ellen Jarred
• Proteomic profiling of the testis-specific epigenetic regulator H2A.B in Hodgkin Lymphoma - Tanya Soboleva
• Painting chromosome territories in mammalian polymorphonuclear cells - Timothy Johanson
• Benchmarking short and long read capture sequencing techniques to identify novel transcripts in genes implicated in neuropsychiatric diseases - Shweta S. Joshi
• A robust new method for measuring telomere length by DNA fibre analysis - Vivian S Kahl
• Taxonomy characterization of ZymoBIOMICS microbial community controls (D6311) on different Illumina NovaSeq read lengths using various metagenomics tools. - Naga Kasinadhuni
• Controlling chromatin compaction by optogenetics - Adele Kerjouan
• Epigenetic modifier Smchd1 is required to maintain a normal pool of long-term repopulating haematopoietic stem cells in mice - Sarah A Kinkel
• Diagnostic outcomes of the Australian genomics brain malformations flagship - Daniz Kooshavar
• Aberrant tRNA adenylation is an early stress response in Saccharomyces cerevisiae - Calvin A Kraupner-Taylor
• Stimulation of cellular activity and DNA secondary structure formation by millimetre waves - Nicholas B Lawler
• Genetic and transcriptomic analysis of brain malformations at single-cell resolution - Wei Shern Lee
• ATRX is required for PML nuclear body integrity in Sertoli cells - Nayla Leon
• Dosage compensation in chicken - Nicholas Lister
• Systematic Functional identification of cancer multi-drug resistance genes - Jamie Littleboy
• Systematic study of circular RNA function using high-throughput screening - Ling Liu
• Genotypic diversity of Salmonella in poultry in Sri Lanka - Nilukshi Liyanagunawardena
• Investigating the role of candidate genes in transgenerational epigenetic inheritance - Dhruv Monteiro
• GCNA interacts with Spartan and Topoisomerase II to regulate genome stability  - Gregory Davis
• Whole blood transcriptome analysis of uncomplicated malaria within Indonesia - Katalina Bobowik