Monday, 17th February 41st Lorne Genome Conference 2020

• No Cell Left Behind: Using Embryoid Bodies to Understand Human Biology - Yoav Gilad
• Investigating the role of structural variation in Brassica disease resistance - Jacqui Batley
• Using ancient epigenomics to reconstruct the anatomy of the elusive Denisovan - Liran Carmel

• Charting genome maintenance and synthetic lethality networks - Daniel Durocher
• Chromosome and chromatin dynamics at DNA Double Strand break - Gaëlle Legube
• Ribosome profiling at isoform level reveals an evolutionary conserved impact of differential splicing on the proteome - Marina Reixachs-Solé (Student Award Winner)

• Preferred long-range and dynamic multi-TAD assemblies in single cells: integrative analysis - Philippe Collas
• DNA G-quadruplexes in human embryonic stem cell and during differentiation - Katherine G Zyner
• Structural variation in the 3D genome folding of mammalian germ cells - Aurora Ruiz-Herrera
• FLIM-FRET reveals distinct roles for HP1α dimers and monomers in chromatin organization - Jieqiong Lou

• Genome-wide discovery of translation control mechanisms - Yoshika Janapala
• CTCF binding at promoters insulates bidirectional transcription - Amanda Khoury
• Nuclear Export of Circular RNA - Vihandha Wickramasinghe
• Epiblast stem cells possess an enhanced capability to mitigate replication stress - Georgia Kafer

• Moving from molecular development to rebuilding a kidney  - Julian Wells Medallist
• Sex-biased genome evolution - Melissa Wilson
• Sponge genomes: windows into evolution of animal development and regeneration mechanisms - Maja Adamska
• Histone H3.3 serine 31 phosphorylation is required for ATRX-mediated heterochromatin maintenance at the telomere - Vinod Benjamin
• Smchd1 is a maternal effect gene required for autosomal imprinting - Iromi Wanigasuriya
• Novel direct targets of JAK2-STAT3/5 signalling in myeloproliferative neoplasms determined by SLAM-seq and ChIP-seq - Charlene Lam
• Evaluation of Oxford Nanopore direct RNA sequencing for gene expression profiling - Josie Gleeson

Melissa Wilson sponsored by University of New South Wales Sydney, School of Biotechnology and Biomolecular Science 

• Advances in repeat expansion disorders: New tools for faster diagnosis and novel gene discovery - Paul J Lockhart
• Molecular and cellular roles of RNA-binding proteins in cardiac biology and disease   - Lithin Louis
• The FANCM-BLM-TOP3A-RMI complex suppresses alternative lengthening of telomeres (ALT) - Robert Lu
• Dissecting the genetic architecture of chronic pain - Mischa Lundberg
• The role of ZBTB7A in foetal globin repression - Lana Ly
• Comapr: An R package for calculating crossover frequency and genetic map construction - Ruqian Lyu
• Analysing Multi-Electrode Array (MEA) data derived from Alzheimer Disease organoids - Tamasha Malepathirana
• Genetically Uncoupling Insomnia from Chronic Pain in Drosophila melanogaster - Joshua N Massingham
• Single-cell RNA-sequencing of differentiating iPS cells reveals dynamic genetic effects on gene expression - Davis J McCarthy
• Identifying blocks free of recombinant haplotypes in human genomes using character-compatibility - Tim W McInerney
• DISSECTING THE ROLES OF N6-METHYLADENOSINE (m⁶A) RNA MODIFICATION READERS IN EMBRYONIC STEM CELLS - Majid Mehravar
• SOX9 controls adhesion and proliferation of Sertoli cells via TYRO3 and TRPC3 - Alejandra Reyes
• A proteomic characterisation of the microprocessor complex in mouse embryonic stem cells - Lawrence Mok
• Whole-genome sequencing identified novel common risk and protective variants of antiseizure medication-induced Stevens-Johnson syndrome in Han Chinese - Kerry Mullan
• The tyrosine phosphatase eyes absent homolog 4 (EYA4) targets polo-like kinase 1 (PLK1) to facilitate successful mitosis - Christopher B Nelson
• Determining the role of maternal epigenetic inheritance in bone development and disease - Ruby Oberin
• Diversity inclusive use of the human reference genome in precision medicine - Hardip Patel
• Decoding fetal liver lineage trajectories at single cell resolution in wild type and Klf1 gene knockout mice - Andrew C Perkins
• Determining the role of maternal epigenetic inheritance in offspring behaviour and brain development - Sigrid R Petautsching
• Polymorphic SVAs are associated with parkinson’s disease progression markers in the PPMI cohort - Abigail L Pfaff
• ZNF827 is a novel single-stranded DNA binding protein involved in the DNA damage response - Hilda A Pickett
• Unravelling the three “-omes” of Pandoraea fibrosis - Miranda E. Pitt
• Evaluating the "-omes" of Extensively Drug-Resistant Klebsiella pneumoniae using Native DNA and RNA Nanopore Sequencing - Miranda E. Pitt
• Multiple links between 5-methylcytosine content of mRNA and translation - Thomas Preiss
• Live cell dynamics of the NF-Y transcription factor - David Priest
• A hierarchical Bayesian model for inference of somatic clonal structure at single-cell resolution   - PuXue Qiao
• Eosinophils directly drive activation of beige adipose tissue - Kate Quinlan
• The epigenetic landscape of the ancient allotetraploid Nicotiana benthamiana - Buddhini Ranawaka
• A universal and independent synthetic DNA scale to measure genetic features - Andre Reis
• Unbiased telomere proteomics identifies novel regulators of ALT telomere maintenance across the cell cycle - Samuel RD Rogers
• Regulation of gene expression by sumoylation in budding yeast - Emanuel Rosonina
• Functional characterisation of 5-(hydroxy)methylcytosine readers associated with CpG-island enhancer regulation in vivo - Samuel Ross
• Secondary Analysis of 1000 Genomes in a Week using 4 servers - Ettikan Karuppiah
• Translation of insulin granule proteins are regulated by PDI and PABP - Rucha Dilip Sarwade
• Genome-wide and targeted multi-omics data analyses to determine the mechanism of Smchd1-mediated gene silencing - Ayush Semwal
• WDR5 is a novel partner of KLF3 and is important in KLF3 genomic localisation and gene regulation - Manan Shah
• High-throughput single cell profiling of transcriptomes and antigen receptors of B and T lymphocytes using nanopore long-read sequencing  - Manu Singh
• Identifying genetic interactors of POWERDRESS - A gene required for plant thermal response - Avilash Singh Yadav
• Deep evolutionary conservation of enhancer DNA methylation dynamics - Ksenia Skvortsova
• The DBHS family of RNA/DNA binding proteins regulate telomerase assembly and recruitment to the telomere - Alexander P Sobinoff
• Distance estimation methods for high-resolution analysis of metagenomic samples - Sean M. Solari
• Packaging mRNA into an mRNP for Nuclear mRNA Export - Katja Straesser
• Analysing DNA Methylation Using Nanopore Long Read Sequencing - Shian Su
• Single-cell genomic analysis of responding B cells in Hepatitis C infection identifies a pathogenic pathway from antiviral immunity towards autoimmunity and lymphoma. - Dan Suan
• Exonic sequencing of reported familial and hemiplegic migraine genes in an Australian patient cohort reveals a diverse spectrum of rare and novel variants - Heidi G Sutherland
• Comprehensive evaluation of human brain gene expression deconvolution methods - Gavin J Sutton
• Molecular mechanisms of radiation-induced cell death - Radoslaw Szmyd
• Exploring nrf2's role in adaptive transcriptional remodelling during liver regeneration - Vicky Tan
• A Smchd1 mutant provides insight into the mechanism of this clinically relevant epigenetic modifier - Andres Tapia del Fierro
• Integrated genomic analyses of CML progression reveal phase-specific mechanisms of structural variant formation - Daniel W Thomson
• Population genomics reveals the structure, diversity, and dynamics of Cryptosporidium hominis spp. worldwide - Swapnil Tichkule
• Using genome editing to introduce naturally occurring deletional mutations associated with elevated foetal haemoglobin as an approach for treating sickle cell disease and β-thalassemia - Sarah Topfer
• Role of pseudogenes in human biology and cancer - Robin-Lee Troskie
• The role of FANCM in fertility and meiosis - Vanessa Tsui
• Systematic identification, validation, and evaluation of breast cancer risk genes through follow-up of genome-wide association studies - Natasha K Tuano
• Exposure of testicular Leydig cells to dibutyl phthalate - a ubiquitous endocrine disruptor - at physiological relevant levels results in downregulation of expression of the androgen receptor gene and of genes involved in chromatin remodeling - Pravesh Tyagi
• Investigating the key mechanisms of alternative polyadenylation - Rachael Turner
• Modeling Evolution of cis Regulatory Elements   - Sonika Tyagi
• Mutations causing Hoyeraal-Hreidarsson syndrome reveal the role of RTEL1 in telomerase-mediated telomere length regulation - Yehuda (Dudy) Tzfati
• A model to study ALTernative Lengthening of Telomeres in cancers - Maheshi Udugama
• Global Analysis of Gene Expression in Differentiating Human Primary Muscle Cells - Akriti Varshney
• Deciphering clonal competition and therapeutic resistance in AML at single-cell resolution using transcribed molecular barcodes - Dane Vassiliadis
• Functional characterisation of archaic hominin introgress in Papua New Guinea - Davide Vespasiani
• Exploring the dynamics of microbial interactions - Rajith Vidanaarachchi
• Adipose tissue beiging is regulated by eosinophils and the transcription factor Krüppel-Like Factor 3 (KLF3) - Emily J Vohralik
• Searching for new factors that mediate chemotherapy-induced peripheral neuropathy - Matthew A Waller
• The Stemformatics atlas: A community platform for integration, visualisation and benchmarking of transcriptome data. - Christine Wells
• Loss of TIP60 abolishes H2AZ lysine 7 acetylation and causes p53, INK4A and ARF-independent cell cycle arrest - Johannes Wichmann
• Activating embryonic globin by genome editing as a therapeutic strategy for alpha thalassemia - Beeke Wienert
• Disruption of mitochondrial factor SDHA-2 affects sperm motility and male fertility in Caenorhabditis elegans - Rachel Woodhouse
• One code to rule them all?  Uniting the histone and transcription factor codes - Kim Woollett
• Validation and targeting of SRP19 in APC deleted cancers - Xinqi Xi
• A 9-gene score for predicting B-ALL risk of relapse and survival - Feng Yan
• Mutation characterisation in patients with Usher syndrome type 2A and application of therapeutic alternative splicing - Khine Zaw
• mitch: An R/Bioconductor package for gene set enrichment of multi-contrast profiling data - Mark Ziemann