In the field of dosage compensation, many studies have only focused on analysing transcriptomic data. The possibility of post-transcriptional dosage compensation has not been considered. The formation and maintenance of proteins requires a variety of processes, ranging from transcription to degradation of mRNA, along with translation, localisation, modification and eventual degradation of the protein itself. Protein abundance requires a dynamic equilibrium of all of these processes. Given the technical challenges of quantifying protein concentration on a large scale, it has become a common practice to make use of mRNA abundance to infer protein abundance. This ignores the possible role post-transcriptional regulation may play in regulating protein abundance. The correlation between ribosomal mRNA associated fragments and protein abundance was higher than for free mRNA abundance and protein abundance. Therefore, these ribosome- associated mRNA molecules were a better indicator of protein abundance than mRNA abundance. Here, we examine the possibility of post-transcriptional dosage compensation through analysing transcription and protein levels. We observe a balancing Z-borne gene dosage between sexes at the protein level in chicken. Whether this phenomenon is true at the translational level remains unknown, but it is evident that post-transcriptional dosage compensation is a possibility for Z-borne genes in chicken.